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SNU Dementia Research Center

Research & Members

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Inhee Mook-Jung, Ph.D

Professor
  • Department of Biochemistry & Molecular Biology
  • Department of Biomedical Sciences
  • Seoul National University, College of Medicine

Contact information

  • Tel

    +82-2-740-8245 (Office)

    +82-2-3668-7636 (Lab)

  • E-mail

    inhee@snu.ac.kr

  • Home page

    Link

Recent Publication (selected)

1.    A breakdown in metabolic reprogramming causes microglia dysfunction in Alzheimer’s disease. Cell Metabolism (2019) 30(3):493-507.

2.    Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer’s disease animal model. Gut (2019) 69(2):283-294.

3.    Plasma tau/amyloid beta1-42 ratio predicts brain tau deposition and neurodegeneration in Alzheimer’s disease. Brain (2019) 142(3):771-786.


Research Interests

1.    Molecular pathogenesis of Alzheimer’s disease

(1)  Abeta-tau axis

(2)  Tau propagation in the brain

(3)  Brain inflammation including microglial function

(4)  Gut-brain axis

(5)  Crosstalk between peripheral and CNS immune system

2.    Identification of plasma biomarkers for early diagnosis of dementia

3.    Therapeutic approaches for Alzheimer’s disease drug development

(1)  Patient-derived brain organoids and microglia

(2)  Platform development of drug screening

(3)  Development of preclinical animal models