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2. Plasma tau/amyloid beta1-42 ratio predicts brain tau deposition and neurodegeneration in Alzheimer’s disease. Brain. 2019;142(3):771-786.
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1. Multi-modal neuroimaging-based cohort study for Alzheimer’s disease (AD)
(1) Identification of biomarkers for the early diagnosis and prediction of AD
(2) Identification of lifetime experiences contributing to AD pathologies
(3) Vascular contributions to AD pathologies (including BBB MR imaging)
(4) Gene-environmental Interaction for AD development
(5) Imaging-genetic approach for AD pathogenesis
(6) Development of instruments for preclinical AD monitoring
2. Clinical trials for anti-Alzheimer biological & non-biological interventions
(1) Anit-amyloid immunotherapies
(2) Anti-amyloid cell therapy
(3) Multi-domain interventions for dementia prevention