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SNU Dementia Research Center

Research & Members

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Manho Kim, MD, Ph.D

Professor
  • Department of Neurology
  • Seoul National University, College of Medicine

Contact information

  • Tel

    +82-2-2072-2193 (Office)

  • E-mail

    kimmanho@snu.ac.kr

Recent Publication (selected)

1.    Altered Vascular Permeability in Migraine-associated Brain Regions: Evaluation with Dynamic Contrast-enhanced MRI. Radiology. 2019 Sep;292(3):713-720

2.    Amelioration of Huntington's disease phenotypes by Beta-Lapachone is associated with increases in Sirt1 expression, CREB phosphorylation and PGC-1alpha deacetylation. PLoS One. 2018 May 9;13(5):e0195968

3.    Gintonin Administration is Safe and Potentially Beneficial in Cognitively Impaired Elderly. Alzheimer Dis Assoc Disord. 2018 Jan-Mar;32(1):85-87


Research Interests

1.    Translational medicine of Neurodegenerative disorders

(1)  Huntington’s disease, Alzheimer’s disease, Cerebellar degeneration

(2)  Exosome as biomarker and delivery tools

(3)  Protein aggregation

(4)  miRNA

(5)  Gut-brain axis and oral microbiotome with ginseng, stillen 

(6)  Blood Brain barrier imaging: Dynamic Contrast enhancement MRI

2.    Huntington’s disease; from in vitro experimental model to clinical trial

3.    Targeting therapeutic strategies in migraine pathogenesis with drug development

(1)  Clinical phase 3 trial with CGRP monoclonal antibody

(2)  Ditan bridging study