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SNU Dementia Research Center

Research & Members

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Yong-Seok Lee, Ph.D

Associate Professor
  • Department of Physiology
  • Department of Biomedical Sciences
  • Seoul National University, College of Medicine

Contact information

  • Tel

    +82-2-740-8225 (Office)

  • E-mail

    yongseok7@snu.ac.kr

  • Home page

    Link

Recent Publication (selected)

1.    Excitatory neuron–specific SHP2-ERK signaling network regulates synaptic plasticity and memory. Sci. Signal. 2019, Vol. 12, Issue 571, eaau5755

2.    Restoring synaptic plasticity and memory in mouse models of Alzheimer’s disease by PKR inhibition. Mol Brain. 2017 Dec 13;10:57

3.    Mechanism and treatment for the learning and memory deficits associated with mouse models of Noonan syndrome. Nat Neurosci. 2014.17(12):p.1736-43

4.    The molecular and cellular biology of enhanced cognition. Nat Rev Neurosci, 2009. 10(2): p. 126-40


Research Interests

1.    Mechanism of memory deficits in genetic disorders

(1)  Mechanism and treatment for RAS pathway-associated diseases

(2)  Cell type-specific signaling networks in the brain

2.    Memory enhancement

(1)  Molecular and cellular mechanism of memory enhancement

(2)  Developing treatment strategy for memory disorders by manipulating plasticity

3.    Circuit mechanism for social deficits