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SNU Dementia Research Center

Research & Members

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Dong Young Lee, M.D., Ph.D

Professor
  • Department of Psychiatry & Behavioral Science
  • Seoul National University, College of Medicine
  • Dementia Clinic, Seoul National University Hospital

Contact information

  • Tel

    +82-2-2072-2205 (Office)

  • E-mail

    selfpsy@snu.ac.kr

  • Home page

    Link

Recent Publication (selected)

1.    Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study. PLoS Med. 2020;17(2):e1003022

2.    Plasma tau/amyloid beta1-42 ratio predicts brain tau deposition and neurodegeneration in Alzheimer’s disease. Brain. 2019;142(3):771-786.

3.    Moderating effect of APOE ε4 on the relationship between sleep-wake cycle and brain β-amyloid. Neurology. 2018;90(13):e1167-e1173.


Research Interests

1.    Multi-modal neuroimaging-based cohort study for Alzheimer’s disease (AD)

(1)  Identification of biomarkers for the early diagnosis and prediction of AD

(2)  Identification of lifetime experiences contributing to AD pathologies

(3)  Vascular contributions to AD pathologies (including BBB MR imaging)

(4)  Gene-environmental Interaction for AD development

(5)  Imaging-genetic approach for AD pathogenesis

(6)  Development of instruments for preclinical AD monitoring

2.    Clinical trials for anti-Alzheimer biological & non-biological interventions

(1)  Anit-amyloid immunotherapies

(2)  Anti-amyloid cell therapy 

(3)  Multi-domain interventions for dementia prevention