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SNU Dementia Research Center

Research & Members

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Dong-Sup Lee, M.D., Ph.D.

Professor
  • Department of Biomedical Sciences
  • Seoul National University, College of Medicine

Contact information

  • Tel

    +82-2-740-8202 (Office)

    +82-2-3668-7625 (Lab)

  • E-mail

    dlee5522@snu.ac.kr

  • Home page

    Link

Recent Publication (selected)

1.    Kidney residency of VISTA-positive macrophages accelerates repair from ischemic injury. Kidney Int. (2020) doi: 10.1016/j.kint.2019.11.025.

2.    Development of α-GalCer Analogues with an α-Fluorocarbonyl Moiety as Th2-Selective Ligands of CD1d. ACS Med Chem Lett. (2019) 10(5):773-779.

3.    Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen. Nat Commun. (2018) 9(1):225.


Research Interests

1.    Tissue-Resident Immune System

(1)  Homeostatic role of tissue-resident macrophages

(2)  Niche-specific immune checkpoint

(3)  Antigen-specific tissue-resident memory T cells

(4)  Immune interaction in the tissue microenvironment

(5)  Role of microglia in neuro-inflammation

2.    Immune Regulation Networks of Innate T Cells and Conventional T Cells

3.    Cancer Immunotherapy through In Situ Immunogenic Cancer Cell Death

(1)  Novel immune checkpoint antibody

(2)  In situ generation of cancer-specific T cells

(3)  Biological & organic nanomaterial guided targeting

(4)  Combinational cancer immunotherapy using a single platform